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CheckMate 025(NCT01668784)研究 -
BIP(NCT02534649)研究 -
PREMIS(NCT03984318)研究
▎小知识:
MC38小鼠结肠肿瘤模型应用广泛,已被证明对PD-1/PD-L1抑制剂有反应。
[1]Bessede A,Marabelle A,Guégan J,et al.Impact of acetaminophen on the efficacy of immunotherapy in cancer patients.Annals of Oncology(2022).
[2]Gocher AM,Workman CJ,Vignali DAA.Interferon-γ:teammate or opponent in the tumour microenvironment?Nat Rev Immunol.2021 Jun 21.
[3]Thomas Kammertoens,Christian Friese,Ainhoa Arina,et al.Tumor ischaemia by interferon-γresembles physiological blood vessel regression.Nature.2021 May 4.
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